Site name Country Principal Investigator Contact email Co – Principal Investigator (Stroke Unit Contact) Minimum dataset feasible now? Consecutive recruitment feasible (admit ≤48h; enrol ≤7d) Expected monthly recruitment Earliest start date Can you hook up patients on EEG MRI during index admission Can you collect and store blood samples to protocol? DTA/DSA status Funding Working groups (pick all that apply) EEG Imaging Biomarker PROMs Notes (optional)
Zurich Switzerland Marian Galovic marian.galovic@usz.ch Andreas Luft Yes Yes 100 January 1, 2027 During the afternoon hours, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 80, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site Required Not applicable — institutional in-kind support only EEG, Imaging, Biomarker, PROMs 10 9 7 8
Semmelweis University, Department of Neurosurgery and Neurointervention Hungary Anna Kelemen odri.abigel@gmail.com Sandor Nardai Yes Yes 90 January 1, 2026 For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 10, De-identified MRI data can be shared for central analysis?, FLAIR, DWI, SWI Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site we don’t understand what DTA/DSA is No local funding yet — local funding not feasible (next 12 months); can start minimum dataset only; central support required for enriched modules EEG, Biomarker, PROMs 1 3 1
Clinica La Sagrada Familia Argentina Carla Diamela Portinari carlaportinari12@gmail.com Julieta Rosales Yes Yes 20 September 29, 2025 During the afternoon hours, For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 20, De-identified MRI data can be shared for central analysis? Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA) Required No local funding yet — local funding not feasible (next 12 months); need central support even for minimum dataset EEG 6 We can perform scalp 30 min EEG at admission, discharge and on follow up. MRI protocol included DWI ADC SWI FLAIR, Laboratory test can be done at admision, discharge and follow up (but not at -80°C)
Universitätsklinik für Neurologie Innsbruck Austria Luisa Delazer and Alexandra Astner-Rohracher luisa.delazer@student.i-med.ac.at Michael Knoflach Yes Yes 60 January 1, 2026 During the afternoon hours, For 30 minutes EEG at the end of hospitalization 70, De-identified MRI data can be shared for central analysis? Can collect, but processing > 2 h or storage above −80 °C, Not currently feasible Required No local funding yet — local funding feasible (≤12 months); can start minimum dataset now; need funds for enriched modules PROMs
Clinical Neurology and SOSD Stroke Unit, Udine University Hospital Italy Mariarosaria Valente mariarosaria.valente@uniud.it Giovanni Merlino Yes Yes 10 October 1, 2025 During the afternoon hours, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 10% Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, If possible, we kindly ask to avoid centralized shipment of laboratory samples so as not to incur the necessity of obtaining DTA/DSA consent. We would require consent for DTA/DSA solely for the purpose of sharing laboratory data. It would be preferable, however, for the laboratory if we could perform the analysis of the samples ourselves. The timelines for obtaining approval for DTA/DSA are very long within our Institution. Not applicable — institutional in-kind support only EEG, Imaging, Biomarker, PROMs 10 2 8 10
Universiti Kebangsaan Malaysia (The National University of Malaysia) Malaysia Ching Soong Khoo chingsoongkhoo@gmail.com OR cskhoo@ukm.edu.my Hui Jan Tan Yes Yes 10 October 1, 2025 During the afternoon hours, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 20, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA), Can collect, but processing > 2 h or storage above −80 °C Required No local funding yet — local funding not feasible (next 12 months); can start minimum dataset only; central support required for enriched modules EEG, Imaging, Biomarker, PROMs
Charité Universitätsmedizin Berlin Germany Jakob Doerrfuss jakob.doerrfuss@charite.de Martin Holtkamp No Yes 20 December 1, 2025 During the afternoon hours 80 Not currently feasible Required No local funding yet — local funding not feasible (next 12 months); need central support even for minimum dataset Imaging
Brno Epilepsy Center Czech republic Irena Dolezalova irena.dolezalova@fnusa.cz Viktor Weiss/Jakub Stefela Yes Yes 15 September 18, 2025 During the afternoon hours, During weekends, For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up?, 12 hours cEEG can be done, but probably in lower number of patients De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA), Can collect, but processing > 2 h or storage above −80 °C Not Required Not applicable — institutional in-kind support only EEG, Imaging, Biomarker, PROMs 7 7 7 6
Maastricht UMC+ Netherlands Rob Rouhl r.rouhl@mumc.nl Yes Yes 20 May 1, 2026 During the afternoon hours 10, De-identified MRI data can be shared for central analysis?, rs-fMRI, DTI (research) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA) Required Not applicable — institutional in-kind support only Imaging, Biomarker, PROMs 3 2 1
NKUA Greece Tsalouchidou Panagiota pania.tsalouchidou@gmail.com Prof. Tsivgoulis Yes Yes 30 June 1, 2024 During the afternoon hours, For 30 minutes EEG at the end of hospitalization 20-30% Not currently feasible Required No local funding yet — local funding not feasible (next 12 months); can start minimum dataset only; central support required for enriched modules EEG, Imaging 8 8
National Cerebral and Cardiovascular Center Japan Kazuki Fukuma k.fukuma@ucl.ac.uk Masafumi Ihara Yes Yes 20 June 1, 2026 During the afternoon hours, For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 80%, De-identified MRI data can be shared for central analysis? Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site Required Local grant submitted / under review EEG, Imaging, Biomarker, PROMs 9 10 8 6 MRI: Our routine inpatient protocol currently includes DWI, ADC, T2*, FLAIR, and MRA. The addition of 3D-T1 (and SWI) during the acute admission period is uncertain at present and may depend on the availability of grant support. Nevertheless, it is more feasible to obtain 3D-T1 imaging at the 3-month follow-up visit, and we will aim to include this sequence whenever possible. EEG: Continuous EEG monitoring for 12 hours is challenging to perform systematically in all consecutive patients. However, it is feasible in selected cases. Blood Samples: We are able to collect and store serum and plasma samples in our local biobank and conduct domestic analyses. The possibility of transferring biospecimens to UZH remains under consideration.
1st Neurology Department, AHEPA University Hospital, Aristotle University of Thessaloniki Greece Vasilios K. Kimiskidis kimiskid@auth.gr Vasiliki Poulidou Yes Yes 10 January 1, 2026 During the afternoon hours, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 90, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site Not Required Not applicable — institutional in-kind support only EEG, Imaging, Biomarker, PROMs 10 8 10 8 With regard to MRI data, we would like to highlight the following: 1) “De-identified MRI data can be shared for central analysis” and 2) “Acquisition of 3D T1 sequences for structural analysis (≤1.5 mm; MPRAGE or similar)” will be feasible only if a radiologist is involved in our team. In addition, to make the data collection more feasible overall, we expect that one more neurologist will join the study.
Hospital de Santa Maria – ULSSM Portugal Carla Bentes ccbentes@gmail.com Teresa Pinho e Melo Yes Yes 20 January 5, 2026 During the afternoon hours, For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up?, qEEG analysis; Sleep EEG 20, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA), Can collect, but processing > 2 h or storage above −80 °C Required No local funding yet — local funding feasible (≤12 months); can start minimum dataset now; need funds for enriched modules EEG, Biomarker, PROMs 1 6 5
Hospital of Lithuanian University of Health Sciences Kauno klinikos Lithuania Giedre Gelziniene giedre.gelziniene@kaunoklinikos.lt Giedre Jurkeviciene Yes Yes 12 December 15, 2025 During the afternoon hours, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 5, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Can collect, but processing > 2 h or storage above −80 °C Required Not applicable — institutional in-kind support only EEG, Biomarker, PROMs 1 3 2
Department of Neurology, Kepler Universitätsklinikum Linz Austria Raimund Helbok Raimund.Helbok@kepleruniklinikum.at Rainer Dormann Yes Yes 50 March 1, 2026 During the afternoon hours, During weekends, For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up?, comment: right now 20min EEGs possible 70, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA), Not currently feasible, comment: has to be organized with the lab and biobank, and how to process blood at night / on weekends has yet to be determined Required No local funding yet — local funding feasible (≤12 months); can start minimum dataset now; need funds for enriched modules EEG, Imaging, Biomarker, PROMs 1 1 1 5 one person from the PSE Linz Team for each subgroup – persons to be announced; planned duration of including patients: 3 months
University Hospital Basel Switzerland Martin Hardmeier martin.hardmeier@usb.ch Joachim Fladt Yes No 10 April 1, 2026 During the afternoon hours, For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 80% Not currently feasible Required No local funding yet — local funding feasible (≤12 months); can start minimum dataset now; need funds for enriched modules EEG 1 yield of prolonged EEG monitoring vs. standard EEG; if funding available 12h cEEG in selected patients possible
Vall d’Hebron University Hospital Spain Laura Abraira laura.abraira@vallhebron.cat Marta Olivé Yes Yes 6 January 3, 2026 For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 30 Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site Required No local funding yet — local funding not feasible (next 12 months); can start minimum dataset only; central support required for enriched modules EEG, Biomarker, PROMs 4 1 1
Joinvasc Brazil Vera Braatz vbraatz@neurologica.com.br Alexandre Longo Yes Yes 50 November 1, 2025 During the afternoon hours De-identified MRI data can be shared for central analysis? Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site Not Required Not applicable — institutional in-kind support only PSE epidemiology
Dep. Neurology, Neurocritical Care, and Neurorehabilitation, Christian Doppler University Hospital, Paracelsus Medical Unievrsity, Österreich Eugen Trinka EUGEN@TRINKA.AT Nele Kapeller and Bernhard Ganser Yes Yes 4 October 12, 2025 During the afternoon hours, During weekends, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 60, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar), ASL Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA) Required No local funding yet — local funding feasible (≤12 months); can start minimum dataset now; need funds for enriched modules EEG, Imaging 10 10
HUB-Erasme Belgium Nicolas Gaspard nicolas.gaspard@hubruxelles.be Gilles Naeije Yes Yes 0 October 1, 2025 During the afternoon hours, During weekends, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 50, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA), sampel collection only during office hours, unless funding is available Required Fully funded — minimum dataset EEG, Imaging 10 10
Modena Italy Stefano Meletti stefano.meletti@unimore.it Guido Bigliardi Yes Yes 20 May 1, 2026 During the afternoon hours, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 20%, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA) Required Local grant submitted / under review EEG, Biomarker 8 10
IRCCS Mondino Foundation Italy Elena Tartara elena.tartara@mondino.it Nicola Davide Loizzo Yes Yes 20 May 4, 2026 During the afternoon hours, During weekends 80%, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA) Required No local funding yet — local funding feasible (≤12 months); can start enriched sub-cohort now with central bridge support EEG, Biomarker 10 10
IRCCS Istituto delle Scienze Neurologiche di Bologna Italy Francesca Bisulli francesca.bisulli@unibo.it Andrea Zini Yes Yes 20 October 1, 2026 During the afternoon hours, For 12 hours cEEG recordings in the acute phase (with 24 hours), For 30 minutes EEG at the end of hospitalization, For 30 minutes at 3 months follow-up? 20, De-identified MRI data can be shared for central analysis?, 3D T1 sequence available for structural analysis (≤1.5 mm; MPRAGE or similar) Serum 10 ml + plasma 10 ml, processed ≤ 2 h, stored at −80 °C on site, Stored samples can be shared for central analysis (de-identified; under Data/Material Transfer/MTA) Required No local funding yet — local funding not feasible (next 12 months); need central support even for minimum dataset EEG, Imaging, Biomarker 10 10 10